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Houston Texans vs. Indianapolis Colts Game Preview: Keys to Victory and In-Depth Analysis


Joe Mixon rushes vs the Indianapolis Colts Week 1
Zach Tarrant/Houston Texans

As the Houston Texans (5-2) prepare to host the Indianapolis Colts (4-3) in a crucial AFC South showdown, the stakes couldn’t be higher. With the Colts just one game behind the Texans in the division, this matchup has massive implications. A Colts win would tie them with Houston for the division lead, while a Texans victory would create a two-game cushion that essentially becomes a three-game lead thanks to Houston’s head-to-head tiebreaker from their Week 1 win in Indianapolis. This pivotal game will play a significant role in shaping the AFC South race and could set the tone for both teams heading into the second half of the season.


Divisional Familiarity: Facing a Foe Twice


Playing a divisional opponent for the second time in a season presents unique challenges and opportunities. The familiarity between the Texans and Colts means both teams have already seen each other’s schemes, personnel, and tendencies, making adjustments from the first matchup critical. Houston narrowly won the season opener, 29-27, behind Joe Mixon’s stellar performance, but the Colts have had time to adapt and will look to counteract the Texans’ strengths.



For Houston, this is an opportunity to not only sweep the Colts for just the second time in franchise history but also create a significant gap at the top of the division standings. On the other hand, the Colts will be motivated to avoid the season sweep and close the gap in the AFC South. The familiarity between these two teams will likely lead to a tightly contested game, where execution and adjustments will be the key to success.


Keys to the Game for the Texans


Offense: Establish the Run and Set Up Play Action


  1. Feed Joe Mixon Early and Often: Joe Mixon, who torched the Colts for 159 yards and a touchdown in Week 1, remains the focal point of Houston’s offense. With the Colts’ run defense ranking near the bottom of the league (allowing 159.9 yards per game), Mixon should see plenty of opportunities to exploit a struggling unit. His physical running style can wear down the Colts’ front seven, setting up manageable third downs for C.J. Stroud and giving the offense a chance to dictate the tempo.


  2. Utilize Play Action to Create Downfield Opportunities: Establishing the run will open up play-action opportunities for C.J. Stroud, who has consistently performed well against the Colts. In his three career games against Indianapolis, Stroud has thrown exactly two touchdown passes and no interceptions each time, demonstrating his ability to exploit their defense. Given Indianapolis’ tendency to commit extra defenders to stop the run, the Texans can capitalize by targeting wide receivers Tank Dell and Stefon Diggs in one-on-one matchups downfield. The Colts have been vulnerable to big plays in the secondary, and Stroud should look to rebound from last week’s struggles by taking advantage of these opportunities.


  3. Protect C.J. Stroud: The offensive line’s ability to keep Stroud upright will be crucial. Last week, Stroud faced heavy pressure and was sacked multiple times, which disrupted the passing game. If the line can hold up and give him time, the second-year quarterback has shown he can deliver in key moments. Incorporating quick passes, screens, and rollouts could help neutralize the Colts' pass rush and keep Stroud comfortable in the pocket.


Defense: Limit the Big Plays and Win on Third Down


  1. Contain Jonathan Taylor: The anticipated return of Jonathan Taylor poses a significant challenge for the Texans' defense. While Taylor has missed the last three games due to an ankle injury, his impact on the field is undeniable. Houston's defense needs to focus on gap integrity and tackle with discipline to prevent Taylor from breaking off explosive runs. Limiting his effectiveness would force the Colts to rely more heavily on Anthony Richardson, which plays into the Texans’ hands.


  2. Pressure Anthony Richardson While Maintaining Containment: Generating pressure on Anthony Richardson will be crucial, but keeping him contained is just as important to prevent big plays with his legs. The Texans’ pass rush has been a bright spot this season, with Danielle Hunter and Will Anderson Jr. leading the way. Hunter has recorded 39 pressures, tied for the most in the NFL, while Anderson has notched 32, ranking sixth. The Texans are the only team to feature two players with at least 30 pressures this season and the only team to have two different players register eight or more pressures in a single game (Week 2 vs. Chicago).


Despite missing several games, Richardson has still managed to rack up 123 rushing yards off scrambles, generating +44 rushing yards over expected, which is the fourth-highest in the league. His efficiency has been notable, with +0.98 expected points added (EPA) per scramble—second-best for players with at least 10 scrambles. Houston's defense has struggled against scrambling quarterbacks, allowing 174 rushing yards and a touchdown, including +62 rushing yards over expected, which is the second-most in the NFL. To succeed, Hunter and Anderson need to apply pressure without overcommitting, forcing Richardson to stay in the pocket and make quick decisions while the interior linemen maintain gap discipline to limit his ability to break free and extend plays.



  1. Win the Battle on Third Downs: Houston's defense struggled to get off the field on third downs in the first meeting, allowing the Colts to extend drives. Improving their third-down defense will be crucial to gaining an edge in this game. By executing timely blitzes and maintaining tight coverage, the Texans can disrupt Richardson's rhythm and give their offense more chances to control the game.


Divisional Rivalry Impact


This game carries significant weight beyond just the records, as the rivalry aspect intensifies the stakes. Divisional games often come down to the smallest details, and mistakes can be magnified in such close matchups. Houston must avoid self-inflicted wounds, such as costly penalties or blown assignments, that can swing the momentum in a tight contest. Additionally, having already beaten the Colts once this season, the Texans can build on the psychological advantage of being the aggressor, while Indianapolis will come in with an urgency to avoid a season sweep.



With a win, the Texans would establish a two-game lead over the Colts, which effectively functions as a three-game advantage thanks to the head-to-head tiebreaker. For Indianapolis, a victory would not only tie them with Houston atop the AFC South but also keep the division race wide open. The outcome of this game could play a pivotal role in determining the eventual division champion, adding even more intensity to an already fierce rivalry.


Final Thoughts


The Texans enter this game with a prime opportunity to solidify their position atop the AFC South and bounce back from a disappointing loss. For Stroud, this is a chance to show resilience and continue his success against the Colts, while Joe Mixon aims to replicate his dominant Week 1 performance. On defense, the Texans will be tested by the potential return of Jonathan Taylor and the unpredictability of Anthony Richardson.

If Houston can establish the run, execute on third down, and play disciplined football, they’ll be in a strong position to sweep the Colts and take a commanding lead in the division. With massive implications in the AFC South standings, this game could be a defining moment in the Texans' push for a playoff berth.





1 Comment


Unknown member
Oct 27, 2024

I'll take the Dub!

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